Studies on LSD-25: Tolerance in Former Morphine Addicts
I. Effects in Former Morphine Addicts and Development of Tolerance During Chronic Intoxication
Harris Isbell and colleagues at the NIMH Addiction Research Center in Lexington, Kentucky, gave LSD daily for up to eighty-five days to former morphine addicts to measure tolerance and compare effects to psychosis. They found rapid tolerance to both physiological and mental effects, which disappeared upon discontinuation.
November 1956
Academic Article
LSD
Harris Isbell