Texts / LSD / Sidney Cohen

Lysergic Acid Diethylamide

Side Effects and Complications

Sidney Cohen surveyed researchers at the VA Neuropsychiatric Hospital who had administered LSD or mescaline to nearly 5,000 subjects across more than 25,000 doses. He found no cases of serious prolonged physical harm and quantified low rates of suicide attempts, psychotic breaks over 48 hours, and other adverse effects.

No. 32

Lisa Bieberman's October 1970 bulletin reviews the two studies then available on whether heavy LSD use damages the brain: Sidney Cohen and Allen Edwards's 1968 neuropsychological tests of thirty users, and William McGlothlin's 1969 attempt to replicate them. Because their results disagree, she concludes there is no evidence of general brain damage. The issue also prints a social worker's letter about how taking LSD changed his work with drug-using teenagers.