The Psychedelic History Archive
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Psychosis

Browse primary sources, people, eras, and related themes connected to psychosis.

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Experimental Compound MER 17 (Frenquel) and LSD-25

Experimental Compound MER 17 (Frenquel) and LSD-25

A 1955 medical film made for the drug company Wm. S. Merrell about Howard D. Fabing's experiments at Christ Hospital in Cincinnati. A 22-year-old graduate student, "Ronnie," takes 100 micrograms of LSD; the film then shows Merrell's compound MER-17 (azacyclonol, sold as Frenquel) given to prevent or reverse the effects. It belongs to the 1950s search for drugs that could block a "model psychosis."